Comprehending HIV and Aids

HIV and Aids are two correlated ailments which have serious consequences for patients. The aim of our discussion today is to understand what each entails and the issues that must be dealt with.

Defining HIV

HIV-budding-Color

First and foremost, HIV is a deadly virus that has a significant impact on the person’s immune system. The immune system is the all-important defense mechanism of the body. Its main objective is to protect the body from diseases. When the body’s natural armor against unfavorable agents becomes comprised, there is a definite cause for concern.

The acronym HIV, which means Human Immunodeficiency Virus, decimates the white blood cell count in the body. These cells are known as T-helper or CD4 and are replaced by HIV, which multiplies once it enters these spaces.

Gradually, the white blood cell count declines as the HIV spreads further. This results in the failure of the immune system to act appropriately. Therefore, an HIV patient would find it increasingly troublesome to deflect diseases since his/her body’s natural defense will fail to do so.

Thankfully, there are legitimate antiretroviral options available to combat HIV in patients, which can afford them a chance at a normal life again. Of course, treatment depends on the stage at which HIV is diagnosed. If the patient is lucky and the diagnosis is done relatively early, then doctors can work their way to better long-term health in patients. This is precisely why regular HIV testing is recommended.

HIV can be found in a person’s semen, blood, body fluids and even breast milk in some cases. It cannot be transmitted through urine, saliva or perspiration. However, individuals must be extraordinarily cautious when they initiate sexual intercourse, as adequate protection is obligatory to avoid transmission of HIV (or any type of sexual disease).

There are other factors which pertain to HIV as well. A contaminated or used syringe can be the cause of HIV. This is why it is imperative to use a sealed and brand new needle to inject any drugs or execute a blood test. Last but not least, women who are expecting and develop HIV, unfortunately, must act promptly. Pregnant females must be aware of the fact that if the virus is situated in their blood, it can easily pass on to the unborn child. Alternatively, the virus may be carried into the child’s body through breastfeeding. Pregnant women must already exercise every caution in the book and this is amplified when motherhood is imminent.

Understanding Aids

Aids and HIV are frequently mentioned in tandem which begs the question: how are they different? Aids is actually the syndrome or symptoms that are caused by HIV.

Aids stands for Acquired Immune Deficiency Syndrome. It is also called advanced HIV or late-stage HIV by doctors. A person with Aids is said to have a weak immune system which is unable to stave off ailments and infections. Aids is essentially the final phase of HIV, which means the infection has manifested itself considerably. The consequences of this can be fatal.

Carriage of HIV

Now that we’ve shared the fundamental details of HIV and Aids, we can shift the focus to learning how it is transmitted from one person to another person.

Human Immunodeficiency Virus is disseminated through a number of ways. The most common theme is that a person may make contact with specific bodily fluids which emanate from a person who has HIV. Examples include the blood of a patient. For instance, if a person is subjected to a syringe which was used by another patient, then the blood of the former may already be contaminating the needle, which is how it could find its way into the bloodstream of the other. Semen can be transmitted through unprotected sex and so can pre-seminal lubricants. A mother may directly affect her infant child through the process of breastfeeding.  

The actual procedure is called HIV transmission. The most common of the aforementioned causes is sexual intercourse. In the US, it is the number one reason for contracting HIV. Obviously, to greatly diminish the likelihood of HIV, individuals must be responsible and use precautions. Condoms are a given and instructions on how to use these are provided with the packaging.

Moreover, agents which do not transmit HIV include basic contact between humans such as exchanging pleasantries or embracing another person. Coming in contact with commodities such as dishes or doorknobs does not mean HIV is transferable (although it is always advisable to wash your hands frequently in order to help avoid any number of other diseases, including the common cold). Foreign carriers such as mosquitoes and fleas, which are known to carry multiple diseases, also do not carry this virus either.

Treating HIV Patients

Antiretroviral therapy can assuage and alleviate is when medication is prescribed which tackles the HIV infection. People who undergo this therapy are required to consume a combination of medicines on a daily basis. They actively prevent the virus from multiplying and replacing white blood cells in the human body. Additionally, the medication vastly reduces the quantity of the virus in the body. Naturally, lesser HIV is tantamount to better health and a greater capability of the body to combat concerns is restored.

In terms of the actual diagnosis, there is a fixed criterion to determine whether a person is suffering from HIV. Tests may indicate that determining a person’s white blood cell. A low count can indicate numerous issues, HIV being one of them. A CD4 count below 200 cells per cubic millimeter is a sign that HIV is at play. The average or healthy count of CD4 ranges from 500 to 1600 cells per cubic millimeter. Alternatively, the other reason may be that the person develops an opportunistic infection, which brings about HIV.

There is no cure for AIDS, but it can be controlled and people can live a fairly normal lifestyle as former NBA star Magic Johnson can attest to. With that said, careful practices during sex and when using injections is paramount to avoid the possibility of contracting this disease.  

 

Alcohol: Society’s Social Enigma

Beer poured in a bottle Maybe Al Capone had it right. No, we are not talking about his hideous crimes, but his (criminal’s and non-criminal’s) ingenuity of realizing that alcohol prohibition was not going to stop the average Joe or Jane from drinking this popular beverage, otherwise known to some as ‘booze’ or  ‘happy juice’.

In chemistry, alcohol is known as an organic compound. Technically speaking, when a hydroxyl functional group is combined with an atom of carbon, it forms alcohol. Let’s dig a little further into this subject and maybe shed some light on it. 

Properties

Ethanol is another name for this stimulant that is commonly found in alcoholic drinks. It is a biphasic drug and different levels of dosage can have varying effects on a person.

It is produced when the yeast ferments sugar in food particles. A known example is wine, which is made from sugar and grapes. Other instances include beer from sugar in malted barley, apple cider and vodka from potatoes and beets.

The content of alcohol varies depending on the type of drink. Fermented drinks like beer contain between 2%-6% of alcohol. This is why, if consumed casually, it does not make a person particularly inebriated. Wine has 8%-20% which makes it a stronger drink. 

On the other hand, drinks like vodka (40%-50%) and tequila (40%) are distilled and have considerably higher toxicity levels.

Effects

Consuming alcohol has an impact on a person’s state of mind. It is a depressant with sedative traits that affect the central nervous system and if consumed in high doses, it can diminish one’s vital functions.

Most consumers associate alcohol with pleasure since drinking small quantities helps improve their mood. How it affects an individual’s frontal lobe can be detrimental to health if taken in large quantities. Which begs the question, is alcohol bad for us?

We can look at the benefits and drawbacks of this intoxicant, which may help us to get an understanding of what makes us want this all inspiring beverage.

Advantages

A commonly held belief among drinkers is that moderate consumption can actually have a positive influence on your health. This belief has been backed by a research conducted at Harvard University.

They accumulated data from over 100 independent studies and concluded that if consumed responsibly, it reduces the risk of diseases such as heart attacks by up to 40%. It also diminishes the possibility of clot-related strokes and other cardiovascular issues, but some drinks can have more positive health benefits than others.

Drinking alcohol increases good cholesterol in your body, which acts as a safeguard against heart disease. It contains high-density lipoprotein (HDL), which has a positive effect on our body.

Moreover, red wine contributes to a reduction in blood pressure since it contains polyphenols. Other health benefits include fighting the common cold. Many infants are given a teaspoon of brandy if they are suffering from influenza. This has been backed by a study at Carnegie Mellon University.

Researchers have also found that alcohol helps improve your sexual health and lower chances of getting long-term illnesses like dementia and diabetes but remember, these studies are based upon moderate drinking. Overdoing it, well, we all know the answer to that!

Disadvantages

 drunk man on alcoholNow that we have elaborated the benefits, we can look at the downside of drinking alcohol – amd there are many. First and foremost, is it important to note that caution is advised when drinking because the more you drink, the greater the chance there is of issues rising, or should we say, there is more of a chance of just plain getting yourself in trouble, to say it mildly.

Many alcohol lovers are prone to heavy and binge drinking, which will be discussed later. If drinking sensibly can help avoid diseases, consuming overwhelming amounts can develop them. As the expression goes – too much of anything can have a negative effect on you.

For instance, drinking too much alcohol can lead to inflammation of the liver, a condition which is called alcoholic hepatitis. Typically caused by viruses, alcohol is identified as one of its major causes. If you are not careful, your liver may also be scarred for life, an issue known as cirrhosis. In addition, jaundice is directly related to excessive alcohol drinking.

Harvard University claims that binge drinking can lead to cancers affecting the breast, colon and of course, the liver. Moreover, alcohol is a known reason for weight gain. One example is beer, which is a calorie-heavy drink and lacks any nutritional value. If it is part of an unhealthy diet, it can cause drinkers to develop a ‘beer belly’ as well.

Drinking also affects your brain capacity. A frequent example is drunk driving. More commonly known as Driving under the Influence or DUI or DWI in the New York area. DUI can result in deadly consequences and we probably know of someone or know someone close to us who went down this road (pun intended). It is not a pleasant experience.

Binge drinking, which we referred to earlier, is a habit of drinking excessive amounts of alcohol. It is a dangerous trend that does not help. If you habitually consume multiple cans or glasses of alcohol in a short time span, it damages the body and increases chances of getting a stroke and blood pressure. Teenagers and millennials are notorious for this and many end up paying the price.

Soft drinks

There are other beverages which have effects which can rival alcohol as well.

Soft drinks like Coca-Cola and Mountain Dew are usually comprised of the following: carbonated water, sweeteners, artificial color, phosphoric acid, caffeine and artificial flavors. The sweeteners have a high level of sugar in them.

It is crystal clear that this is not a healthy blend of ingredients at all. Soft drinks also have zero nutritional value. In other words, it is a hollow drink with empty calories and no apparent advantage. Caffeine is a diuretic. That means it causes a greater occurrence of urine. This, in turn, means that chances of dehydration are greater. Sodas are also weight gainers.

The only potential benefit of soft drinks is that it contains the aforementioned caffeine and elements of sugar, which can give you a lift if you’re low on energy. However, it is better to have fruits such as apples which have the same effect.

Furthermore, excess intake of sugar is quite detrimental. People often read the nutritional value of foods and consume it without thinking twice if the fat percentage is negligible. In such cases, it is important to note that the sugar level of such foods may be quite high, which is never a good idea.

A single, 350 milliliter can of Coke contains 39 grams of sugar. That is equal to roughly 9 teaspoons of sugar. This means it is bad for your bones since it reduces the calcium level in your body.

Diet soda, which is advertised as having no sugar, is not a viable alternative either. They have an abundance of sweeteners, which leads to sugar cravings and potential weight gain.

Conclusion

William Hogarth - Gin Lane
Beer Street and Gin Lane, 1751 William Hogarth 1697 – 1764
The most obvious caveat from our discussion is that both alcohol and soft drinks have multiple drawbacks. However, in the case of the former, it has a number of health benefits too.

We have discussed the attributes, advantages, and disadvantages of alcohol in detail and the bottom line is simple. Be happy. Have fun and have a shot or two, but also be reasonable. Losing your cognitive abilities can put you in many places, none of which will make you proud. Additionally, you can become vulnerable to any number of crimes, including becoming a victim of sexual abuse. Other people’s lives may be put in jeopardy as well. Think about it. 

Can You Replace Healthy Food with Supplements


Can Vitamins replace food for good health?
Photo by fikmik – yayimages.com

Most  Americans have a busy schedule and don’t have time to eat a well-balanced diet. In scenarios like this, popping a multivitamin can seem to be an easy way out to meet the nutrition requirements.  

Statistics show that around 68 percent of US adults take dietary supplements. What’s more, around 84 percent of the consumers show confidence in the effectiveness and safety of the supplements. Vitamin supplements seem to be the perfect solution to get the required nutrients and continue with the daily routine or are they?

However, the fact is that supplements can never compare to wholesome food.

According to a spokesperson for American Dietetic Association, D. Milton Stokes, a supplement cannot provide all the benefits of consuming food items. They simply are not food substitutes.  

Dangers of Relying on Supplements

Supplements can’t replace whole food. You should not replace meals by taking vitamin supplements. While supplements can be taken to meet vitamin deficiency, they should not be considered an alternative to whole food.  

Furthermore, contrary to what some people believe, supplements are not 100 percent natural. Side effects can occur if you try to meet the daily vitamins and minerals requirement by taking the pills. They are particularly harmful to children who can experience dangerous side effects.  

In order to fulfill the vitamin and nutrition requirements, it is important that you implement a well-balanced diet plan. Consider following these five simple tips to stay healthy:

  1. Include lots of vegetables and fruits in the diet.
  2. Consume rice, bread, and other food items high in starch. Prefer bread made of whole grain flour instead of white bread.
  3. Avoid or limit intake of refined starch foods. Also, limit intake of food items high in sugar and fat.
  4. Eat dairy food items such as yogurt and milk.
  5. Include fish, beans, and eggs, in your daily diet.

Vitamin supplements should be treated as nothing more than supplements. They should complement your diet instead of replacing wholesome food items. For instance, vitamin D supplement should be taken by all breastfeeding and pregnant women, senior individuals, and children. Also, taking folic acid supplement is recommended for pregnant women in order to prevent issues with the neural tube.  

Conclusion

You should adopt healthy eating habits to remain in good mental and physical shape. The diet should include healthy whole food items. A healthy diet and exercise are essential for a healthy body and mind. You should always cut down on salt, sugar and saturated fat. In addition, drinking about 8 glasses a day is essential. Other than that, you should take vitamins and minerals supplement only to meet the deficiency that is not fulfilled with the daily diet. Relying on the supplements alone is not a wise choice.  

The Risk of Bad Sleep Habits on Your Health

Humans require sleep just as they require oxygen, water, and food to survive. Adequate hours of sleep are vital for the health. However, the demands of the fast-paced city life make it difficult for many of us to get adequate sleep at night.

The National Sleep Foundation recommends that an adult individual should get at least seven hours of sleep every night. Not getting enough sleep at night does not just result in drowsiness and fatigue. Various studies have shown that lack of sleep leads to increased risk of various health disorders.

Sleep Deprivation and Health Risks

Our sleep needs vary as we age. We require fewer hours of sleep as we age. However, the demands of the daily life make it difficult for most people to get the required hours of sleep at night. Sleep deprivation leads to increased risk of various health disorders some of which are briefly discussed below.  

1. Diminished Cognitive Process

Sleep plays an important role in improved cognitive process. Inadequate sleep at night impairs mental processes. This leads to reduced alertness, focus, and decreased problem-solving and reasoning skills. As a result, a person’s productivity is adversely affected while performing tasks during the day. Also, impaired mental functioning increases the risk of accidents when driving or operating heavy machinery.

2. Increased Risk of Health Disorders

Lack of sleep puts a person at increased risk of heart attack, heart failure, high blood pressure, irregular heartbeat (arrhythmia), stroke, and diabetes. Around 90 percent of the people that have been diagnosed with insomnia, or chronic inability to sleep at night, also suffer from one of these health complications.

3. Reduced Libido

Lack of sleep also has been linked to reduced libido in both men and women. Sleep-deprived people show less interest in sex due to sleepiness, stress, and depleted energy. Studies have shown that men with sleeping problems also may have low testosterone levels that lead to reduced interests in sex with the partner.

4. Depression and Anxiety

A survey conducted in 2007 of 10,000 individuals found that sleep-deprived people were five times more likely to develop depression. People with sleep problems are more likely to develop depression and anxiety disorders as compared to those that have adequate hours of sleep at night.

5. Premature Aging

Lack of sleep can also lead to premature aging of the skin. People that do not get adequate sleep at night develop fine lines and dark circles under the eyes. When persons do not get adequate sleep at night, it results in the release of the stress hormones. This hormone contributes to aging of the skin.

In conclusion, you should make sure to get 7 to 9 hours sleep every night. Consider consulting with a general physician for sleep therapies or medications for getting oversleep troubles. However, most of the people would benefit by making slight changes in the daily habits that result in getting adequate hours of sleep during the night.

COPD: The Disease Leonard Nimoy Lived With

Less than a month after taking to Twitter to urge fans to quit smoking, Leonard Nimoy died at the age of 83 from chronic obstructive pulmonary disease (COPD), a lung disease that makes breathing difficult.

Best known for playing Spock on Star Trek, Nimoy spent his last weeks reminding fans of the dangers of smoking through Twitter. The actor had quit smoking 30 years earlier, but not soon enough, he tweeted. Nimoy had announced last year that he had been diagnosed with the disease.

COPD is almost always caused by smoking, which accounts for as many as 9 out of 10 COPD-related deaths, according to the Centers for Disease Control and Prevention. Continuing to smoke after being diagnosed will only escalate the damage of COPD.

In the early stages of the disease, patients experience a nagging cough, shortness of breath, wheezing, and tightness in the chest. Nimoy passed away from end-stage COPD, which includes severe airflow limitation and exacerbations.

After he died, his wife confirmed that end-stage COPD was the cause of death. However, this is not the cause with everyone at this stage of the disease. A study in 2008 found that more COPD patients die with their disease rather than from it.

COPD most commonly occurs in people age 40 years and older who have a history of smoking. The disease restricts airflow for a number of reasons: the airways in the lungs lose their ability to stretch and shrink; the walls between many air sacs are destroyed; the walls of the airways become irritated and swollen; the airways make more mucus, which clogs them and blocks airflow.

People with COPD are told to stop smoking, plan special activities that strengthen the muscles used for breathing, use medicines such as a bronchodilator or inhaled steroid, or in serious cases surgery can be recommended.

Drug Usage Continues to Climb Amongst Teenagers

Although not a disease, we thought it important to talk about this subject, since is is so prevalent in our society. The use of drugs has increased over all in our society, but the prevalence among teenagers is alarming. The teenagers have no need to indulge in these activities, yet they somehow end up being a part of this act and often get addicted to drugs at a very young age. The most common reasons why teenagers use drugs include:

  • Peer Pressure

One of the most common reasons why teenagers firstly try and then get hooked to drugs is due to peer pressure. The constant pressure from their friends, seniors, and other people of their age often leads many teenagers to try drugs just so that they can feel included. Many times bullies involve younger teenagers at schools to try out drugs as a challenge. Out of the fear of being left out and ridiculed, teenagers try drugs out. And this develops into a continuous habit in many cases.

  • Seeing Others

Teenagers often see other adults trying out a drug which gives them a feeling of thrill or excitement and they want to try it on their own. Many times, this is done out of curiosity as well. If parents openly smoke, drink alcohol, or abuse other drugs in front of their children, the children eventually follow the footsteps as observed in many research studies as well. The influence of the social circle and neighborhood that the teenagers are a part of also plays a very important role.

  • To End Boredom or To Express Rebellion

Many teenagers adopt drugs as a sign of rebellion against their lifestyle, family life, social norms, or environment in general. Being considered a taboo, drugs are prohibited in such a young age. As they say that “forbidden fruit is the sweetest”, hence, teenagers often try drugs to stand against the general norms. In some cases, teenage try drugs out of boredom or just for the sake of trying. This turns into drug abuse in most of the cases.

  • Repetitive Promotion in Media

Drugs are portrayed as attractive substances and often deemed to be cool in various media channels, especially music. Many Rap songs are actually promoting the use of drugs, and this is establishing a drug culture in a way. Young minds, without understanding the consequences and only blinded by the pseudo attractions, end up using drugs.

  • To Boost Self-Esteem

As we just mentioned, drugs are often perceived to be ‘cool’ by many teenagers. The ones who have low self esteem or do not have much confidence, they use drugs to feel good and improve their perception about themselves. This also gives them an excuse or safe way out in case they do something to embarrass themselves.

There are many more reasons that add up to the list. Many of them can be addressed through better research and proper educative awareness programs, especially in school.

Assuring Patients Can Receive Timely Quality Care

New York physicians continue to pay liability premiums that far exceed those in any other state. After liability premiums for New York physicians shot up 55-80% between 2003 to 2008 before the Legislature intervened to impose rate freezes in 2008 and 2009, medical liability premiums have continued to steadily rise. Many New York physicians continue to pay outrageous liability premiums that far exceed $100,000, and some even exceed $300,000! The cost of medical liability coverage for the 2014-15 policy year was:

• $338,252 for a neurosurgeon in Nassau and Suffolk counties;
• $186,639 for an OB/GYN in Bronx and Richmond counties;
• $132,704 for a general surgeon in Kings and Queens counties; and
• $134,902 for an vascular surgeon or cardiac surgeon in Bronx and Richmond counties.

Malpractice payouts in New York State continue to be far out of proportion to the rest of country. For example, in 2013, according to a report by Diederich Healthcare and reported in the March 15, 2014 Washington Post, New York State had by far and away the highest number cumulative medical liability payouts ($689,800,300), nearly two times greater than the state with the next highest amounts, Pennsylvania ($356,855,500), and far exceeding states such as California ($274,590,800) and Florida ($199,442,450). Additionally, New York State had by far and away the highest per-capita medical liability payments in the country, far exceeding the second highest state Pennsylvania by 57%, the third highest state New Jersey by 67%, and the fourth highest state Massachusetts by 74%.

We can no longer sustain such an expensive, inequitable, and fatally flawed medical liability adjudication system if we wish to assure that our healthcare system will be able to accommodate the demand that will inevitably come as our population ages and becomes more resource-dependent, as well as the nearly 1,000,000 newly insured patients who are starting to receive coverage through New York’s new health insurance Exchange. We need comprehensive reform of our flawed civil justice system and reduction in our medical liability costs, not legislation that increases costs and exacerbates existing problems.

We support legislation to create alternative systems for resolving medical liability cases, such as medical court or a Neurologically Impaired Infants No-Fault fund. We also strongly support legislation to enact medical liability tort reforms enacted in other states which would: place reasonable limits on non-economic damages; identify and assure qualified expert witnesses; eliminate joint and several liability; identify a physician supplying a Certificate of Merit; immunize statements of apology or regret; and provide immunity for physicians providing pro bono care.

Preventing Untenable Expansions of Liability MSSNY will continue to strenuously oppose any measure to expand the damages recoverable in medical liability actions, including legislation that would: • Create a “date of discovery” rule for New York’s statute of limitations for medical liability actions – Estimated to increase premiums by 15%;

• Expand “wrongful death” damages to permit “pain and suffering” – Estimated to increase premiums by 53%;
• Permit the awarding of pre-judgment interest – Estimated to increase premiums by 27%;
• Eliminate the current statutory limitations on attorney contingency fees in medical liability cases – Estimated to
increase premiums by over 10%;
• Prohibit ex-parte interview by defense counsel of the plaintiff’s treating physician;
• Change loss-share rules regarding non-settling defendants.
Enactment of any of these measures would have calamitous consequences on our health care system. Efforts to reform our medical liability adjudication system must be comprehensive!

Muhammad Ali and Parkinson’s Disease

Doctors think the head trauma Muhammad Ali suffered during his boxing career might have contributed to his Parkinson’s disease. Approximately 1.5 million Americans have Parkinson’s disease and 60,000 more are diagnosed with it each year. Boxing may have influenced Ali’s disease, but the data are far from conclusive. His family has suggested that his disease was due to the exposure to pesticides he had experienced earlier in life. But the truth is that we may never know what caused his Parkinson’s—or that of the vast majority of those diagnosed.

Parkinson’s Disease is a neurodegenerative disorder in which cells in a part of the brain that controls movement begin to die. As a result, patients slow down, lose coordination, and tremble.

Ali referred to his condition as a “trial” from God and spoke of preparing for death. He said he thought about it during each of his five daily prayers, but he did not give the impression it prayed on his mind. If anything he seemed at peace with the idea.

He would say that speaking in public was something he had to strive to overcome: “I realize my pride would make me say no, but it scares me to think I’m too proud to appear in public  because of my condition.”

Ali never complained. He would wake, shower and sit in his arm chair watching old boxing reels.  There were no complaints.  No time blaming others for his fate. “He would always say to his family, ‘These are the cards I was dealt, so don’t be sad.”  

How did Ali stay so positive? “He would say, ‘I’ve got the best-known face on the planet. I’m the three-time heavyweight champion of the world. I’ve got no reason to be down.”

Ali will be remembered as more than just “the greatest”.  He was a powerful force on humanitarian missions. He spoke out against racism, war and religious intolerance, while projecting an unshakable confidence that became a model for African-Americans at the height of the civil rights era and beyond.

Ali was known to be a friend of the Jewish people.  Although he railed against Jewish promoters at times and slammed ‘Zionist control of the world’, he also attended his grandson’s bar-mitzvah and appealed to Muslim extremists to release Jewish journalist Daniel Pearl. In an article in USA Today, written by Ali’s good friend, Billy Crystal, boycotted a country club after being told they did not allow Jews.  Ali never attended that club again.

Through expert care, research and grants, it is the goal of the Parkinson’s Foundation and patients everywhere to make the world a better place for people suffering with Parkinson’s until there is a tomorrow without this dreadful disease.

157 Pregnant Women in the US Being Monitored for Zika Virus Infections

The number of pregnant women in the US with the Zika virus is going up as the Centers for Disease Control and Prevention (CDC) reevaluates how it reports cases.

Previously, pregnant women with an asymptomatic Zika virus infection who do not have known pregnancy complications were not reportable. However, the CDC established new surveillance systems to monitor pregnancies and congenital outcomes among women with laboratory evidence of Zika infections but no symptoms.

As of May 12, 157 pregnant women in US states and 122 pregnant women in US territories were being monitored for evidence of possible Zika virus infection. These systems are monitoring clinical presentation of the infection, all prenatal testing, and adverse consequences of the virus during pregnancy in order to better understand the risk for congenital infection and the spectrum of adverse congenital outcomes.

“These data will improve clinical guidance, inform counseling messages for pregnant women, and facilitate planning for clinical and public health services for affected families,” according to the CDC’s Morbidity and Mortality Weekly Report.

The criteria for the Zika virus among asymptomatic or symptomatic pregnant women include the presence of fever, rash, arthralgia, or conjunctivitis, Guillain-Barré syndrome, or an adverse pregnancy outcome, such as fetal loss or in utero findings of microcephaly. The clinical criteria for Zika virus congenital infection in infants include microcephaly, intracranial calcifications, or other central nervous system abnormalities.

Among the 157 women in the states being monitored, only 49% reported clinical symptoms consistent with Zika virus and among the 122 pregnant women in the US territories, 66% reported clinical symptoms.

“Limiting surveillance to symptomatic women with confirmed or probable Zika virus disease or to women already affected by an adverse pregnancy outcome excludes a substantial proportion of women with asymptomatic and possible Zika virus infection during pregnancy,” according to the report.

However, the expanded definition being used can also overestimate Zika virus infection among pregnant women being screened because of crossreactivity with dengue and other, similar viruses.

“Findings from these U.S. surveillance systems are expected to improve understanding of Zika virus infection during pregnancy, enhance risk assessment and counseling of pregnant women and families, advance clinical care, and assist states and territories to anticipate and plan needed resources and increase prevention efforts,” the report concluded.

Gene Mutations and Cancer Risk

Image of woman holding her chest with pink banner next to her
Pixabay

Since Angelina Jolie opened up about her BRCA1 gene mutation, more awareness about this mutation is spreading. Due to her announcement, public awareness skyrocketed and more women were getting tested. So much so that it became a phenomenon known as the Angla Joli Effect.

What Are the Chances of Getting Breast Cancer if You Have the BRCA1 Gene?

Those who test positive for an abnormal BRCA1, BRCA2, or PALB2 gene are learning their chance for breast cancer is higher than that of the average woman. An average woman without the mutation only has a 12% chance of getting breast cancer in her lifetime according to the  National Cancer Institute, whereas a woman with BRCA1 or BRCA2 has up to an 85% chance of getting breast cancer in her lifetime. The chance for ovarian cancer also increases with the gene mutations to about 16-44% chance compared to just under 2% for the average woman without the mutation. Women with BRCA1 are also more likely to develop estrogen-negative cancers, meaning that a cancer’s growth is not caused by the hormone estrogen. Anti-estrogen hormone therapy is not a viable treatment option and since these cancers tend to be more aggressive it’s important they are caught early. BRCA2 mutation-caused cancers however can benefit from hormonal therapy according to the American Cancer Society.

BRCA1, BRCA2 Prevention

This information is incredibly important because it gives women a chance to lower their risk through a variety of methods starting with an annual breast MRI at age 25. This is of great significance as BRCA1 and BRCA2 cancers tend to be aggressive and it is important to catch them early. Other risk-lowering methods include prophylactic surgery such as a double mastectomy and oophorectomy.

BRCA1 and BRCA2 not only affect women, but men are also at risk. Men with BRCA1 or BRCA2 mutation have an increased chance of developing prostate cancer and a higher lifetime risk of developing male breast cancer. Both women and men with the mutation are also at an elevated risk of developing pancreatic cancer. Those with a family history of breast or ovarian cancer should consider being tested for these mutations. Those with  Ashkenazi Jewish ancestry are also more likely to have the BRCA1 or BRCA2 mutation.  

The PALB2 gene mutation increases the chance of breast cancer to about 58% percent. Research about this gene is ongoing to find out how it affects the likelihood of developing other cancers such as ovarian and pancreatic.